Cialis – Lilly ICOS Wonder Drug

A slow and steady revolution is sweeping the market for erectile dysfunction drugs – Cialis. Most people may not even be aware of it. Lilly ICOS, the pharmaceutical alliance, which launched the blockbuster drug Cialis, announced that the drug has achieved 1 billion dollars in global sales since launching in Europe less than two years back.

In fact Cialis has become the top Erectile Dysfunction treatment in France, since January 2005, based on the latst market data, easily overtaking Viagra, the first brand to be launched in this market. It is also doing very well in United Kingdom, Italy, Germany, United States, Canada, Australia, Mexico and Brazil.

So much so that a Lilly ICOS press release contained these words from Rich Pilnik, President of Lilly’s EMEA region “We are very pleased with the performance of Cialis and the steady development of the brand since its launch two years ago. Millions of men suffer from ED and the growth of the market demonstrates that patients are speaking to their healthcare providers about ED and seeking treatment options.”

Not only has Cialis been able to expand the market but it has also eaten heavily in the market share of Viagra from Pfizer, the first drug to be launched in this market and Levitra from Glaxo-Bayer-Schering Plough. In fact Cialis was the second PDE5 inhibitor drug to become available in Europe. It is currently promoted in approximately 100 countries including the United States, Australia, Brazil, Mexico, Canada and across Europe and Asia for Erectile Dysfunction.

According to Paul Clark, Chairman and Chief Executive Officer of ICOS Corporation.
“Passing the $1 billion mark is an important milestone for Lilly ICOS and a great accomplishment for the Cialis team. Since 2003, men with erectile dysfunction have had a choice of oral treatments for their condition – a condition which may impact on relationships and daily life.”

Beyond all the hype and the jubilation is the sheer superiority of Cialis over all the other drugs available in this indication. To understand the benefits of Cialis, we need to firstly understand this complex condition.

Erectile Dysfunction or Impotence is defined as the inability to ensure and maintain an erection sufficient for sexual intercourse. ED affects an estimated 180 million men worldwide . 90 percent of ED cases are related to a physical or medical condition, such as diabetes, cardiovascular diseases, and prostate cancer treatment, while 10 percent are due to psychological causes . In many cases, however, both psychological and physical factors contribute to the condition.

Where physical factor play an important role PDE-5( Phosphodiaterase) inhibitors have a significant role to play. These include drugs like Sildenafil (Viagra) and Vardenafil(Levitra). But none are as good as Tadalafil(Cialis). Why?

Firstly let’s understand how PDE-5 inhibitors work. They work by inhibiting the enzyme phosphodiasterase-5 which is responsible for degrading another enzyme called cGMP(cyclic Guanosine Mono Phosphate) which through a series of reactions is responsible for the synthesis of nitric oxide. Nitric oxide is an important vasodilator responsible for dilation of the blood vessels that supply blood to the penis. Thus, there is an increase in the blood supplied to the penis and this increased blood engorges the penis and leads the formation of an erection through hydraulic pressure.

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Generic Cure

Why Brand the Generic?

When the branded drug becomes a generic drug, what takes shape is a cure that becomes readily available for the many deprived, since the price of the drug falls drastically with the transition. Cheap Generic drugs thus become a challenge to the branded versions and with the help of internet pharmacy reaches you within no time. Online generic drugs open the box of cure that till then had been only within the reach of the branded. The reason is due to the lesser cost that goes behind the research and development of the generic as well as the stiff competition that exists between the large number of generic drug manufacturers. You now needn’t have to be rich to afford the cure to diseases where the drugs had been patented. Generic solves the hurdles with the same content and the same cure as the branded. To buy generic drugs is hence to buy the cure.

Pharmacy Online

Online generic drugs and internet pharmacy goes hand in hand; the need for the drug is felt by the click of the mouse. There even exist methods whereby the drugs could be prescribed online with the help of active medical units in the web world. You could try visiting online France pharmacy. You could at times be advised to change the branded with a generic drug by your pharmacists. What he means is good for you since it is not the coating of the drug or the color or shape which matters rather the dosage strength, manufacturing control and the labeling that define the generic drug. This under stringent requirements is tested and inspected by the authorities to remain the same and hence there needn’t be a lack of confidence in buying the generic version.

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